Особенности вызванной активности мозга при оценке эмоционально окрашенных сцен у девушек с разными генотипами полиморфизма Val158Met (G472A) COMT

Екатерина Михайловна Ковш; Павел Николаевич Ермаков; Елена Викторовна Воробьева

doi:10.21638/11701/spbu16.2016.315

Authors

Екатерина Михайловна Ковш Academy of Psychology and Educational Sciences, Southern Federal University, 13, pr. M. Nagibina, Rostov-na-Donu, 344038, Russian Federation
Павел Николаевич Ермаков Academy of Psychology and Educational Sciences, Southern Federal University, 13, pr. M. Nagibina, Rostov-na-Donu, 344038, Russian Federation
Елена Викторовна Воробьева Academy of Psychology and Educational Sciences, Southern Federal University, 13, pr. M. Nagibina, Rostov-na-Donu, 344038, Russian Federation

DOI:

https://doi.org/10.21638/11701/spbu16.2016.315

Abstract

Th e article presents the results of a study on the spatio-temporal and amplitude characteristics of stimulated brain activity in ranking emotionally-charged scenes in 61 right-handed women, aged from 18 to 24 years, with diff erent genotypes of structure of the gene and the brain mechanisms involved in the assessment of emotionally-charged stimuli, are describedVal158Met (G472A) COMT polymorphism (GG connotes high activity of the enzyme COMT, the average level of dopamine in the prefrontal brain areas; GA middle ranking COMT activity with an above average dopamine level; AA low activity of the enzyme COMT with a high concentration of dopamine in the prefrontal brain cortex). The contemporary view of the Val158Met (G472A) polymorphism of COMT gene functions and its links with emotional, cognitive and personality characteristics are considered. The relationship between the specifi cs of the structure of the gene and the brain mechanisms involved in the assessment of emotionally-charged stimuli, are described.

Keywords:

psychogenetics, VEPs, gene СOMT, dopamine, prefrontal brain cortex, amygdala, emotions

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References

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