Особенности физиологических механизмов когнитивных функций у  больных шизофренией с  различной фармакотерапией

Иван Анатольевич Горбунов; Кристина Андреевна Чепикова; Александр Александрович Гаевский; Дмитрий Петрович Яничев

doi:10.21638/11701/spbu16.2018.106

Authors

Иван Анатольевич Горбунов 1 St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
Кристина Андреевна Чепикова 1 St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
Александр Александрович Гаевский St. Petersburg state public institution “Psychiatric Hospital No. 6”, 9, Obvodnovo Kanala nab., St. Petersburg, 191167, Russian Federation
Дмитрий Петрович Яничев 1 St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation

DOI:

https://doi.org/10.21638/11701/spbu16.2018.106

Abstract

The article describes results of the study of the neurophysiological mechanisms of cognitive functions associated with the parameters of various cognitive styles. Subjects included schizophreniс patients with paranoid attacks and healthy people. Subjects also made up two groups based on the intake of various types of neuroleptics. Methods: psychological techniques for measuring cognitive styles, SANS. The ERP to different sequences, consisting of standard and deviant stimuli. Results: We have found changes in the neurophysiological mechanisms of cognitive functions depending on cognitive styles and the intake of various types of neuroleptics. Neurophysiological mechanisms of cognitive functions are associated with the short-term memory system and the work of the hippocampal structures that provide the potential of neuronal synapses.

Keywords:

prediction, cognitive styles, EEG, event related potentials, pharmacotherapy, typical antipsychotics, atypical antipsychotics, implicit learning, explicit learning, neuroimaging

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References

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